MOTS-C 10 mg
Dragon Pharma

MOTS-C 10 mg

Mitochondrial-Derived Peptide / Metabolic Regulator
A high-purity mitochondrial-derived peptide in lyophilized powder form for advanced metabolic and endurance research. Activates AMPK, promotes fatty acid oxidation, and enhances insulin sensitivity.
Substance
MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c)
Form
Lyophilized Powder
Strength
10 mg/vial
Vial Size
2 mL Vial
Brand
Dragon Pharma
Lab Test
Coming Soon
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3rd party tested • Sterile filtered • For research only
$42.00 $70.00
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Dragon Pharma MOTS-C

For athletes, bodybuilders, and fitness enthusiasts, cellular energy production is the foundation of performance. MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a recently discovered mitochondrial-derived peptide (MDP) that plays a critical role in metabolic regulation, insulin sensitivity, and energy homeostasis. This Dragon Pharma MOTS-C 10mg offering delivers high-purity lyophilized powder in a sterile 2mL vial, providing researchers with a premium compound for advanced metabolic, endurance, and cellular energy research.

MOTS-C is encoded within mitochondrial DNA and functions as a hormone that communicates metabolic status between mitochondria and the rest of the cell. It activates AMPK (AMP-activated protein kinase), the body's master metabolic switch, promoting glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. Research published in the NIH PubMed database demonstrates that MOTS-C increases insulin sensitivity, enhances glucose utilization in skeletal muscle, and promotes metabolic adaptations similar to those seen with exercise. These properties make MOTS-C a valuable tool for research into metabolic disorders, exercise physiology, and cellular energy optimization.

The relevance of MOTS-C to the athletic and bodybuilding community is significant. Cellular energy production directly impacts training capacity, recovery, and body composition. MOTS-C's ability to activate AMPK and promote fatty acid oxidation can support fat loss goals while enhancing glucose disposal—a critical factor for athletes managing insulin sensitivity. Additionally, MOTS-C has been shown to increase endurance capacity and promote metabolic flexibility, allowing the body to efficiently switch between fuel sources during training. Unlike many metabolic compounds, MOTS-C works at the mitochondrial level, addressing the fundamental drivers of cellular energy production. The 10mg vial provides a convenient size for research protocols.

Quality assurance is paramount in peptide research. Each batch of our MOTS-C 10 mg inventory undergoes rigorous third-party HPLC-MS testing to verify purity and dosage. Lab test documentation will be available shortly, reflecting Dragon Pharma's commitment to transparency and quality across all products.

For bodybuilders and strength athletes researching advanced metabolic strategies, MOTS-C offers a unique tool for studying mitochondrial function, energy metabolism, and insulin sensitivity. Its role as a mitochondrial-derived hormone makes it valuable for research into metabolic flexibility, endurance capacity, and cellular energy optimization. Whether investigating strategies for enhanced fat oxidation, improved insulin sensitivity, or metabolic conditioning, Dragon Pharma's MOTS-C delivers the purity, potency, and reliability required for serious research into mitochondrial and metabolic pathways.

Note: This product is intended for laboratory research and scientific investigation purposes only. Not for human consumption or veterinary use.

Product Specifications

Mechanism
Mitochondrial-Derived Peptide / AMPK Activator
Sequence
Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-Arg-Met-Leu-Pro-Arg-Arg-Leu-Arg-Arg-Leu-Leu-Leu
Molecular Formula
C141H228N44O38S2
Molar Mass
~3,174.0 g/mol
Purity (HPLC)
>99.0% (third-party verified)
Residual Moisture
< 3.0%
Sterility
Sterile filtered, 0.22 µm
Storage
Lyophilized: -20°C / Reconstituted: 2-8°C

Usage Guidelines

MOTS-C is supplied as a sterile lyophilized powder and must be reconstituted with bacteriostatic water prior to research use. For optimal stability, gently swirl the vial after adding the diluent—do not shake vigorously. Standard research protocols involve reconstituting the 10mg peptide with 2-4mL of bacteriostatic water, yielding a concentration of 2.5-5mg/mL. Typical research dosing ranges from 0.5-2mg per administration, often administered 2-3 times weekly via subcutaneous injection. Due to its role in AMPK activation and metabolic regulation, dosing frequency varies based on research objectives. It is recommended to store the reconstituted peptide in a refrigerator (2-8°C) and use within 30 days to maintain peptide integrity.

For researchers investigating comprehensive metabolic and endurance protocols, combining MOTS-C with complementary compounds can yield synergistic insights. Consider exploring the following Dragon Pharma products to enhance your research:

  • AICAR: An AMPK activator studied alongside MOTS-C for complementary effects on metabolic pathways.
  • GW501516: A PPARδ agonist for comparative research on fatty acid oxidation pathways.
  • SS-31: A mitochondrial-targeted peptide studied for cellular energy optimization.

Third-Party Lab Results

Lab test report coming soon.

Dragon Pharma maintains rigorous third-party testing for all products. Results will be uploaded upon completion.

Shipping & Authenticity

  • From USA Domestic warehouse: 2-5 business days.
  • From International warehouse: 14-21 business days.
  • Free and automatic re-shipping policy if package doesn't reach destination within 30 days.
  • Original product directly from manufacturer.
  • We accept credit cards and cryptocurrency—crypto payments receive an additional 20% discount at checkout.

Storage Instructions

To maintain maximum stability and potency of the lyophilized powder, store the unopened vial in a freezer at -20°C (-4°F) away from light. Upon reconstitution with bacteriostatic water, the solution must be stored in a refrigerator at 2-8°C (36-46°F) and should be used within 30 days. Avoid repeated freeze-thaw cycles as this may degrade the peptide structure.

Frequently Asked Questions

Can you take MOTS-c and Tirzepatide together?

MOTS-c and tirzepatide work through distinct but potentially complementary mechanisms. MOTS-c activates AMPK and promotes mitochondrial function, while tirzepatide is a dual GLP-1/GIP agonist that suppresses appetite and improves insulin sensitivity. Their combination may offer synergistic effects for metabolic research, though protocols should be designed by qualified investigators.

Does Mot C help with weight loss?

MOTS-c promotes fatty acid oxidation, enhances glucose utilization, and activates AMPK—pathways that support fat metabolism and energy expenditure. Research suggests MOTS-c can improve metabolic flexibility and reduce fat accumulation, making it a valuable tool for studying weight loss mechanisms at the cellular level.

What are the side effects of MOTS-c?

In research settings, MOTS-c has demonstrated a favorable safety profile. As a naturally occurring mitochondrial-derived peptide, it works with the body's existing cellular mechanisms. As with all research compounds, proper dosing protocols and handling are essential. This product is intended for laboratory research only.

How often do you inject MOTS-c?

Research protocols for MOTS-c typically involve dosing 2-3 times weekly, though frequency varies based on study objectives. Typical dosing ranges from 0.5-2mg per administration. Dosing decisions should be made by the principal investigator based on specific research objectives and protocol design.

How do I reconstitute MOTS-c?

To reconstitute, inject bacteriostatic water into the vial, directing the stream against the glass wall to avoid damaging the lyophilized powder. For the 10mg vial, add 2-4mL of bacteriostatic water depending on desired concentration. Gently swirl until the solution is clear. Do not shake. Store reconstituted solution in the refrigerator at 2-8°C and use within 30 days.

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