For athletes, bodybuilders, and fitness enthusiasts seeking to understand the fundamental mechanisms of energy metabolism, endurance, and body composition, AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) represents a unique research tool. As a potent activator of AMP-activated protein kinase (AMPK)—the body's master metabolic switch—AICAR offers researchers a way to study cellular energy homeostasis, glucose uptake, and fatty acid oxidation pathways. This Dragon Pharma AICAR 50mg offering delivers high-purity lyophilized powder in a sterile 2mL vial, providing researchers with a premium compound for advanced metabolic and endurance research.
AICAR functions by mimicking AMP (adenosine monophosphate), activating AMPK—a key cellular energy sensor that regulates metabolic pathways. When activated, AMPK promotes catabolic processes that generate ATP (such as fatty acid oxidation and glucose uptake) while inhibiting anabolic processes that consume ATP (such as lipid synthesis and protein synthesis). Research published in the NIH PubMed database demonstrates that AICAR increases glucose uptake in skeletal muscle, enhances fatty acid oxidation, and can even induce metabolic adaptations similar to those seen with endurance training—including mitochondrial biogenesis and increased exercise capacity. These properties have made AICAR a cornerstone compound in metabolic research.
The relevance of AICAR to the athletic and bodybuilding community is significant. Understanding how AMPK activation influences energy metabolism has profound implications for body composition optimization. AMPK activation promotes fat oxidation, which can support fat loss goals, while also influencing insulin sensitivity and glucose disposal. Additionally, the compound's ability to induce metabolic adaptations similar to endurance training offers researchers a unique tool for studying exercise mimetics and mitochondrial function. For athletes, understanding these pathways can inform strategies for metabolic conditioning, fat loss, and overall energy efficiency.
Quality assurance is paramount in research compounds. Each batch of our AICAR 50 mg inventory undergoes rigorous third-party HPLC-MS testing to verify purity and dosage. Lab test documentation will be available shortly, reflecting Dragon Pharma's commitment to transparency and quality across all products.
For bodybuilders and strength athletes researching advanced metabolic strategies, AICAR offers a unique tool for studying AMPK-mediated pathways. Its role in fatty acid oxidation, glucose uptake, and mitochondrial biogenesis makes it valuable for research into fat loss, metabolic health, and endurance adaptations. Whether investigating strategies for enhanced fat oxidation, improved insulin sensitivity, or metabolic conditioning, Dragon Pharma's AICAR delivers the purity, potency, and reliability required for serious research into cellular energy metabolism.
Note: This product is intended for laboratory research and scientific investigation purposes only. Not for human consumption or veterinary use.
AMPK ActivatorAICAR is supplied as a sterile lyophilized powder and must be reconstituted with bacteriostatic water prior to research use. For optimal stability, gently swirl the vial after adding the diluent—do not shake vigorously. Standard research protocols involve reconstituting the 50mg peptide with 2-5mL of bacteriostatic water, yielding a concentration of 10-25mg/mL. Typical research dosing in preclinical studies ranges from 0.5-5mg per administration, often administered daily or every other day via subcutaneous or intraperitoneal injection. Due to its role in AMPK activation, dosing protocols vary based on research objectives. It is recommended to store the reconstituted peptide in a refrigerator (2-8°C) and use within 28 days to maintain peptide integrity.
For researchers investigating comprehensive metabolic and endurance protocols, combining AICAR with complementary compounds can yield synergistic insights. Consider exploring the following Dragon Pharma products to enhance your research:
Lab test report coming soon.
Dragon Pharma maintains rigorous third-party testing for all products. Results will be uploaded upon completion.
To maintain maximum stability and potency of the lyophilized powder, store the unopened vial in a freezer at -20°C (-4°F) away from light. Upon reconstitution with bacteriostatic water, the solution must be stored in a refrigerator at 2-8°C (36-46°F) and should be used within 28 days. Avoid repeated freeze-thaw cycles as this may degrade the compound.
AICAR is a potent activator of AMP-activated protein kinase (AMPK), the body's master metabolic switch. It is studied for its effects on glucose uptake, fatty acid oxidation, mitochondrial biogenesis, and metabolic adaptations similar to endurance training. It is used in research on metabolism, exercise physiology, and body composition.
In research settings, side effects vary based on dosing protocols. Preclinical studies have noted effects related to AMPK activation, including potential impacts on cardiac function at very high doses. Proper dosing protocols and monitoring are essential. This product is intended for laboratory research only.
AMPK activation promotes fatty acid oxidation and inhibits lipid synthesis, making it a key regulator of fat metabolism. Research suggests AMPK activation can support reductions in adipose tissue, including visceral fat, by enhancing the body's ability to oxidize fatty acids for energy. AICAR is studied as a tool to activate AMPK and investigate these pathways.
AICAR has been shown to increase endurance capacity in research models by activating AMPK, which promotes mitochondrial biogenesis, enhances fatty acid oxidation, and improves glucose uptake. These adaptations mimic some of the effects of endurance training, making AICAR a valuable tool for studying exercise mimetics and metabolic conditioning.
To reconstitute, inject bacteriostatic water into the vial, directing the stream against the glass wall to avoid damaging the lyophilized powder. For the 50mg vial, add 2-5mL of bacteriostatic water depending on desired concentration. Gently swirl until the solution is clear. Do not shake. Store reconstituted solution in the refrigerator at 2-8°C and use within 28 days.
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